Sangi Apagard Premio is a premium Japanese toothpaste featuring nano hydroxyapatite (nano mHAP), a re-mineralizing agent designed to support enamel smoothness and surface repair, with a minimal or zero abrasive formulation for gentle daily brushing.
This high-end Apagard toothpaste is known for its higher-than-standard nano mHAP concentration, making it a flagship option within the Apagard series for advanced enamel care, daily oral hygiene support, plaque control, and long-term tooth surface maintenance.
It also contains liquid conchiolin, a pearl-derived ingredient, which contributes to a smoother tooth surface feel and added natural luster and gloss after brushing.
What are the differences between Apagard M Plus, Smokin', Premio, and Royal?
All three are formulated mineral nanoparticles to promote healthier tooth enamel, but they differ in emphasis:
- M-plus: Standard daily care toothpaste, balanced formula for general oral hygiene, enamel support, and everyday use
- Smokin': Stain-focused formula designed for stronger removal of coffee, tea, and nicotine-related surface discoloration while supporting enamel care
- Premio: Premium high-concentration nano mHAP formula with approximately 1.4x higher content than the other variants, positioned for enhanced enamel care, smoother tooth surface feel, and advanced daily protection
- Royal: Premium balanced care formula positioned between M-plus and Premio, offering enhanced daily enamel support with a refined feel for regular use
- High concentration nano hydroxyapatite (nano mHAP) formula
- Minimal or zero abrasive composition for gentle brushing
- Liquid conchiolin pearl ingredient for smooth surface and gloss effect
- Supports enamel surface care within daily oral hygiene routine
Wet your toothbrush and apply a pea-sized amount of toothpaste. Brush all surfaces of your teeth for at least 2 minutes, making sure to reach each area evenly. After brushing, spit out the toothpaste and rinse your mouth thoroughly with water. For best results, use twice a day as part of your regular oral care routine.
- Net contents: 105g
- Format: Protected aluminum laminated tube with one-touch cap.
- Made in Japan
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Large selection of curated, high-quality products
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Most affordable prices in the market
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Rapid shipping, no matter the location
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In-house customer service by phone, chat or email
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Loyalty program & membership benefits
- Effectiveness
- Taste
- Value
- Quality
- Texture
- CGCatalina G.Verified BuyerRated 5 out of 5 stars7/27/26Great Quality Toothpaste
I think I'm poised to only buy Japanese toothpaste from now on😛; the quality of this toothpaste seems so much higher than any of the ones I've ever bought in the US 💕
- KTKirill T.Verified BuyerRated 5 out of 5 stars7/2/26One more...
I’ve been using Sangi Apagard Premio Premium Hydroxyapatite Toothpaste and I’m really pleased with it. It leaves my teeth feeling very clean and smooth, and I like that it feels gentle during daily use. I also haven’t noticed any gum irritation, which is very important for me. The taste is pleasant and not too strong, and my mouth feels fresh after brushing. Overall, it gives a great impression and feels like a high-quality toothpaste for enamel care.
- RBRakesh B.Verified BuyerRated 5 out of 5 stars5/21/26High quality toothpaste
Very good at strengthening enamel, noticeably stronger than Sensodyne
- MFMohammad F.Verified BuyerRated 4 out of 5 stars5/7/26Started to see results
Its hardly been 10 days since i received it, i have teeth attrition and it seems that after i started using this toothpaste its now less visible. Something is happening and the results seem good. Shipping cost is a little too expensive, if they can use Chinese logistics to get it delivered it might get more affordable
- CTcristiane t.Verified BuyerRated 5 out of 5 stars5/4/26Excellent
Very good, reliable toothpaste.
- ALAnthea L.Verified BuyerRated 5 out of 5 stars3/27/26Second Order
AN excellent product! I read many reviews for Hydroxyapatite Toothpaste brands before making my first order and am very satisfied with the product and the price!
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